Blackstone Valley Obstetrics & Gynecology

200 Commerce Drive

Northbridge, MA 01534

Phone: 508-234-6260

Fax: 508-234-0764

View map of this location

M-F: 8:30am - 5pm
S-Su: Closed - Closed

We see patients off-site on Tuesday evenings. Please note that while we are open for patient visits during the hours listed above, our phones may be covered by our answering service for the first and last half-hours of our business day. Our office is closed on most major holidays.

Blackstone Valley Obstetrics & Gynecology

Blackstone Valley Obstetrics & Gynecology at Milford Regional in the Blackstone Valley is committed to providing quality health care to the women of the Blackstone Valley in a warm and compassionate environment. Our practice consists of two providers. As a husband and wife team with twenty years experience in labor, delivery, urogynecology and pelvic reconstructive surgery, Dr. Samuel Zylstra and Brenda Zylstra are trained to evaluate total female health needs. They provide personal health care and are specially trained in the medical and surgical management of obstetrics and female pelvic floor disorders. They are both board certified in their respective areas.


Dr. Zylstra and Brenda Zylstra, NP are sub-specialists in urogynecology (also called female pelvic medicine and surgery). Your doctor may recommend that you see other sub-specialists such as infertility, perinatology or gynecologic oncology. Most referrals require your primary care physician to evaluate and refer you.


Medical Records

If you need a copy of your medical record, please download our Medical Record Release Form.  Print, complete, and return it to Milford Regional Physician Group via mail or fax as indicated on the form.



We are providers for most medical insurance plans. Because there are a wide variety of insurance options, please contact your insurance company directly to make sure your doctor accepts your plan.  We provide equal access to our patients regardless of the source of payment.
If you are insured, please remember to bring your insurance card with you when you visit our office. We must validate your insurance at each visit. Your co-payment is due at the time of your visit. We accept check, Mastercard, Visa, Discover and American Express.  If you are uninsured, please visit the Massachusetts Health Connector website.


Patient Education

As a patient, it is crucial that you understand your medical condition as well as related procedures and treatment.  To help patients recall and fully understand information that your Milford Regional Physician Group provider shared with you during a visit, we have created short patient education videos.  Please click on the topic that you are interested in below.  You will be connected to another website and see your provider's profile page.  In order to access the video, please select on the desired topic under "Watch my vidscrips".  For more videos by Milford Regional Physician Group providers, you may visit our Patient Education page.

Incontinence Evaluation - Samuel Zylstra, MD, MPH, FACOG

Hospital Affiliations

Our primary hospital is Milford Regional Medical Center.

The Milford Regional Physician Group Network of Doctors​

Blackstone Valley Obstetrics & Gynecology is a Milford Regional Physician Group facility. Milford Regional Physician Group is a physicians’ practice group serving the healthcare needs of residents in MetroWest and the Blackstone Valley. Our physicians, physician assistants and nurse practitioners practice primary and specialty medicine in office locations within Bellingham, Franklin, Hopedale, Hopkinton, Medway, Mendon, Milford, Northbridge and Upton. For a free guide to our many fine healthcare providers, please call 508-473-1480.

Providers At This Practice

Connect with Milford Regional Physician Group